Tb500 5Mg

TB-500 (Thymosin Beta-4) | Regenerative Peptide

The “Cellular Migration” Accelerator

TB-500 is a synthetic version of the naturally occurring 43-amino acid peptide, Thymosin Beta-4 (T$\beta$4). While often compared to BPC-157, TB-500 operates on a more systemic level, primarily through its ability to regulate actin polymerization. This fundamental cellular process allows cells to move and reorganize, making TB-500 a critical tool in research involving wound healing, muscle recovery, and cardiovascular repair.

Systemic Mobility: Unlike localized repair factors, TB-500 can travel through the circulatory system to find and target damaged areas.
Actin Regulation: A primary regulator of the cell’s cytoskeleton, facilitating rapid cellular migration to injury sites.
Anti-Fibrotic Potential: Studied for its ability to reduce scar tissue formation and improve functional recovery.

Mechanism of Action

TB-500’s primary biological role is sequestering G-actin (monomeric actin):

Cytoskeletal Reorganization: By modulating actin, TB-500 promotes the migration of “reparative” cells (such as keratinocytes and myofibroblasts) to the site of an injury.
Angiogenic Stimulation: It increases the production of matrix metalloproteinases, which helps break down tissue barriers to allow for the growth of new blood vessels.
Inflammatory Modulation: Acts to down-regulate pro-inflammatory cytokines, creating a more favorable biochemical environment for tissue regeneration.
Dermal & Corneal Repair: Research shows significant acceleration in the healing of skin and ocular surface injuries through enhanced cell epithelialization.

Potential Research Applications

Muscle & Connective Tissue Repair: Investigating the recovery rate of acute muscle tears and chronic tendinopathies in animal models.
Cardiovascular Regeneration: Exploring the peptide’s ability to promote heart tissue repair following ischemic events.
Hair Growth Studies: Researching the activation of stem cells in the hair follicle to stimulate growth and thickness.
Arthritic Research: Studying the protection and repair of joint cartilage and the reduction of localized joint inflammation.

Technical Specifications

CAS Number: 77591-33-4
Molecular Formula: C_{212}H_{350}N_{56}O_{78}S_{1}
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Purity: >99\% Research Grade
Disclaimer: Research Use Only

This product is strictly for laboratory research and in vitro studies only. It is not for human or veterinary use. All handling must be performed by qualified professionals in a controlled environment according to local safety regulations.